Principal Scientist, Human Genetics (African Genomics Program) 

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Company Details
Industry: Pharmaceuticals
Description: Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare - a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims for improving patient access to medical innovations by working with all relevant stakeholders. Twenty-nine medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology; Life Sciences Industry eight years in a row by the Dow Jones Sustainability Indices (DJSI). The Roche Group, headquartered in Basel, Switzerland, is active in over 100 countries and in 2016 employed more than 94,000 people worldwide. In 2016, Roche invested CHF 9.9 billion in R&D and posted sales of CHF 50.6 billion. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan
Job Description

Key Challenges

 

Spearhead analysis of genetic and genomic data gathered from African and African-descent populations to uncover novel biology, in close collaboration with our academic collaborators and with the human genetics and computational teams within Roche

 

Identify and characterize genetic disease risk, progression, and therapeutic responses in African- and African-descent populations

 

Utilize large-scale experimental and computational capabilities, including AI/ML, to place genetic findings in their functional context.

 

Implement research strategies to translate these insights into novel opportunities for therapy, prevention and diagnosis

 

Lead efforts in target identification, causal inference, biomarker discovery, and clinical strategies, working closely with our research and clinical development teams to prioritize and advance targets into therapeutic development.

 

Contribute to a collaborative community involving research biology, clinical development, translational medicine, and computational sciences teams.

 

Who You Are as an Ideal Candidate

 

You are a PhD with a strong focus on statistical genetics, genetic epidemiology, or related fields, and strong proficiency in the development and/or application of statistical methods

 

Strong computational skills, including large-scale data analysis and causal inference.

 

5-10 years of experience using human genetics to understand diseases, in academia and/or industry with a focus on association studies in ancestrally-diverse cohorts

 

Recognized leader in your field, equivalent to an assistant professor at a top research university.

 

Excellent research record with scientific publications in top-tier journals.

 

Passionate about leveraging emerging African data sets to solve biological questions and deliver health care advances.

 

Exceptional communication and interpersonal skills to present and explain findings to diverse audiences (excellent written & spoken English are essential). 

 

Proven ability to deliver compelling external presentations

 

Motivated to thrive in a fast-paced, collaborative research environment

 

Ability to operate independently, be an active proactive problem solver and demonstrate strong critical thinking and systems awareness.

 

Ability to travel 

 

 

 

Education: Degree, Diploma
Employment Type: Full Time

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