Wes Burns gave the home team the lead in the fifth minute and Conor Chaplin completed a flowing move to make it two just before the break.
Marcus Harness scored Ipswich's third goal midway through the second half from close-range.
Sheffield Wednesday manager Xisco Munoz is in danger of the sack after a 1-0 defeat against West Bromwich Albion at The Hawthorns.
Just months after promotion from League One, an eighth loss from 10 league games left bottom-of-the-table Wednesday with their worst ever start to a season.
John Swift's 13th-minute goal settled the contest and the Owls have gone 312 minutes without a goal.
Stuart Armstrong's sublime free-kick handed Southampton successive league wins with a hard fought 1-0 victory at Stoke.
Isaiah Jones and Emmanuel Latte Lath netted in the second half to give Middlesbrough a 2-0 win against Cardiff at the Riverside Stadium.
The Bluebirds had won four in a row, but Jones grabbed his first league goal of the season in the 56th minute before Latte Lath wrapped up Middlesbrough's third successive victory with six minutes left.
Birmingham powered to a 4-1 demolition of Huddersfield at St Andrew's as Siriki Dembele's brace and goals from Koji Miyoshi and Jordan James ended the hosts' barren run.
Millwall claimed a 2-0 win at Plymouth thanks to second half goals from Zian Flemming and George Saville.
