Nkunku came off the bench and made an assist in Leipzig's 3-0 win away at Wolfsburg in mid-February.
The former Paris Saint-Germain forward, who has been linked with a possible move to the Premier League in summer, has since made two appearances off the bench including the 1-1 draw with Manchester City in their Champions League Last 16 first leg match.
Rose said at his eve of match press conference he did not hold a grudge against Dortmund, who sacked him in May 2022, after just one season in charge, despite a second-placed finish.
"It is what it is. I don't have the feeling that I was negatively impacted," he said.
"Things worked out in such a way that I'm now the coach in Leipzig."
Leipzig-born Rose took over after the sacking of Domenico Tedesco in early September and has since picked up 37 points in 17 games, a better record than any other club in the Bundesliga.
Dortmund come into the match equal on points atop the Bundesliga table with Bayern Munich after a nine-match winning streak.
Leipzig sit four points back in fourth place.
"Dortmund's winning streak and the confidence that it gives them makes them very tough opponents," said Rose.
"They've put a great run together and have a lot of individual quality.
"We will need to work hard to deal with the power and the force that Dortmund have going forward."
๐ฆ๐ฒ๐บ๐ฎ๐๐ผ๐ฐ๐ถ๐ฎ๐น ๐ถ๐ ๐๐ต๐ฒ๐ฟ๐ฒ ๐ฟ๐ฒ๐ฎ๐น ๐ฝ๐ฒ๐ผ๐ฝ๐น๐ฒ ๐ฐ๐ผ๐ป๐ป๐ฒ๐ฐ๐, ๐ด๐ฟ๐ผ๐, ๐ฎ๐ป๐ฑ ๐ฏ๐ฒ๐น๐ผ๐ป๐ด. Weโre more than just a social platform โ from jobs and blogs to events and daily chats, we bring people and ideas together in one simple, meaningful space.